OMICRON
What is it and How is it diff from other variants?
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The Omicron variant called as variant B.1.1.529 is a new variant which was first reported to WHO on 24 November 2021 and was classified as a variant of concern by WHO on 26 November 2021.
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This variant has shown a very large number of mutations, especially more than 30 on the viral spike protein, which is the key target of the immune response.
DETECTION
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The most accepted and commonly used method of diagnosis for SARS-CoV2 Variant is RT-PCR method.
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This method detects specific genes in the virus, such as Spike (S), Enveloped (E) and Nucleocapsid (N) etc to confirm the presence of virus.
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However, in case of Omicron, as the S gene is heavily mutated, some of the primers may lead to results indicating absence of the S gene (called as S gene drop out).
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This particular S gene drop out along with the detection of other viral genes could be used a diagnostic feature of Omicron.
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However, for final confirmation of the omicron variant genomic sequencing is required.
PRECAUTIONS TO BE TAKEN
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Wear a well-fitted mask over your mouth and nose.
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Take both doses of vaccines (if not yet vaccinated).
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Maintain social distancing.
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Cough or sneeze into a bent elbow or tissue.
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Clean your hands frequently.
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Maintain good ventilation to the maximum possible.